Genome-Wide Local Ancestry and Mitonuclear Coadaptation in African Hybrid Cattle

doi:10.1016/j.isci.2022.104672

Genome-Wide Local Ancestry and Mitonuclear Coadaptation in African Hybrid Cattle

iScience

paper

Using MOSAIC local ancestry inference to uncover mitonuclear coadaptation in admixed Bos taurus/indicus populations.

Published

June 27, 2022

James A. Ward, Gillian P. McHugo, Michael J. Dover, Thomas J. Hall, Said Ismael Ng’ang’a, Tad S. Sonstegard, Daniel G. Bradley, Laurent A.F. Frantz, Michael Salter-Townshend, and David E. MacHugh have published a paper in iScience:

Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populations (Bos taurus/indicus)

Applying local ancestry inference across admixed African cattle breeds, we find significantly elevated taurine nuclear ancestry at genes whose protein products interact directly with mitochondrially encoded proteins—providing genome-wide functional evidence for mitonuclear coadaptation in hybrid mammals.

Citation

BibTeX citation:

@article{2022,
  author = {},
  title = {Genome-Wide {Local} {Ancestry} and {Mitonuclear}
    {Coadaptation} in {African} {Hybrid} {Cattle}},
  journal = {iScience},
  date = {2022-06-27},
  url = {https://doi.org/10.1016/j.isci.2022.104672},
  doi = {10.1016/j.isci.2022.104672},
  langid = {en}
}

For attribution, please cite this work as:

“Genome-Wide Local Ancestry and Mitonuclear Coadaptation in African Hybrid Cattle.” 2022. iScience, June. https://doi.org/10.1016/j.isci.2022.104672.